acetylation by p300 inhibits the glycosylase activity of human NEIL2 while it stimulates the glycosylase activity of OGG1

eotid metabolism Fatty acid metabolism, lipid metabolism IDH2 qq P48735 Mitochondria Isocytrate metabolism, tricarboxylic acid metabolism, glyoxylate cycle 7 Proteome of Victims of Suicide METABOLISM Gene IDH3A Protein name Isocitrate dehydrogenase 3 subunit alpha, mitochondrial Inositol-1monophosphatase 1 NADH dehydrogenase Fe-S protein 1, 75kDa NADH dehydrogenase FeS protein Pyruvate dehydrogenase alpha 1 Protein disulfide isomerase family A, member 3 Phosphoglycerate kinase 1 Up/down regulation q Accession number Cellular localization P50213 Mitochondria Molecular function Carbohydrate metabolism, tricarboxylic acid cycle +IMPA1, NDUFS1 Q Q P29218 P28331 Cytoplasm Mitochondrial inner membrane space, respiratory chain complex I Mitochondria Mitochondria Cytoplasm Phosphate metabolism, phosphatidylinositol biosynthesis, signal transduction ATP metabolism, transport, electron transport, ROS metabolism, apoptosis NDUFV2 +PDHA1 PDIA3 Q qqq qq Q6IPW4 O00330 P00558 NAD binding Pyruvate metabolism Glycolysis, phosphorilation PGAM1 Phosphoglycerate mutase 1 QQ,, PGLS PKM2 TALDO1 UCHL1 6-Phosphogluconolactonase QQ Pyruvate kinase isozymes M1/M2 Transaldolase 1 qq q P18669 O95336 P14618 P37837 P08559 Cytosol Cytoplasm Cytoplasm, nucleus Cytoplasm Mitochondria Respiratory burst, glycolysis, pentose-phosphate shunt Pentose-phosphate shunt Glycolysis, programmed cell death Pentose shunt Glycolysis, pyruvate metabolism Ubiquitin carboxyl-terminal qq esterase L1 Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial Ubiquinol-cytochrome c reductase core protein II Cytochrome b-c1 complex subunit 2, mitochondrial qqqq UQCRC2 P22695 Mitochondria Electron transport, respiratory chain, proteolysis, transport, oxidative phosphorylation PROTEIN PROCESSING Gene BRCC3 Protein name BRCA1/BRCA2-containing complex, subunit 3 Lys-63-specific deubiquitinase BRCC36 Capping protein muscle Z-line, alpha 2 FK506-binding protein 4, 59kDa Heat shock cognate 71 kDa protein Heat shock 27kDa protein 1 Vps20-associated 1 homolog Up/down regulation q Accession number Cellular localization P46736 Nucleus Molecular function DNA repair, modification-dependent protein catabolism, Ubl conjugation pathway CAPZA2 q Cytoplasm Chaperon protein folding +FKBP4, +HSPA8, HSPB1 VTA1 q qQ Q02790 P11142 Cytoplasm, nucleus Cytoplasm Protein binding, HSP binding, FK506 binding, peptidyl-prolyl cis-trans isomerase activity Chaperone, response to unfolded proteins, membrane organization, interspecies interaction between organisms, post-Golgi vesicle-mediated transport Anti-apoptosis, cell death, cell motion, response to heat, response to unfolded proteins, regulation of translational initiation Protein transport Q P04792 Cytoplasm, nucleus, cytoskeleton 24074843 Cytoplasm, endosome, cell membrane q Q9NP79 DEVELOPMENT Gene +DPYSL2,,,,, Protein name Dihydropyrimidinase-like 2 Up/down regulation qqq Accession number Cellular localization Q16555 ZM 447439 site Cytolplasm Molecular function Cell differentation, nervous system development, nucleotide and nucleic acid metabolism, intracellular trafficking of heterooligomeric forms of steroid hormone receptors 8 Proteome of Victims of Suicide DEVELOPMENT Gene +SELENBP1,, 8941386 SEPT2 SEPT3, +SEPT5, SIRT2 TPD52 TPD52L2 Protein name Up/down regulation Accession number Cellular localization Q13228 Cytoplasm, membrane, nucleus Cytoplasm, cytoskeleton, nucleus Synapse, nucleus, cell junction Plasma membrane, septin complex, synaptic vesicle Cytoplasm, microtubul

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