Product Name :
17-(Allylamino)-17-demethoxygeldanamycin, 99%
Synonym:
IUPAC Name :
(4Z,6E,8R,9R,10E,12R,13S,14R,16R)-13-hydroxy-8,14-dimethoxy-4,10,12,16-tetramethyl-3,20,22-trioxo-19-[(prop-2-en-1-yl)amino]-2-azabicyclo[16.3.1]docosa-1(21),4,6,10,18-pentaen-9-yl carbamate
CAS NO.:
75747-14-7
Molecular Weight :
Molecular formula:
C31H43N3O8
Smiles:
CO[C@@H]1C[C@H](C)CC2=C(NCC=C)C(=O)C=C(NC(=O)C(C)=C/C=C/[C@@H](OC)[C@H](OC(N)=O)C(C)=C[C@@H](C)[C@@H]1O)C2=O
Description:
17-(Allylamino)-17-demethoxygeldanamycin (17-AAG) inhibits heat shock protein 90 (Hsp90), the expression of heat shock factor-1, and the activity of oncogenic proteins such as N-ras, Ki-ras, c-Akt, and p185erB2.Rifapentine In addition to its anti-tumor effects, 17-AAG also induces apoptosis.Chloroquine phosphate PMID:23537004 MedChemExpress (MCE) offers a wide range of high-quality research chemicals and biochemicals (novel life-science reagents, reference compounds and natural compounds) for scientific use. We have professionally experienced and friendly staff to meet your needs. We are a competent and trustworthy partner for your research and scientific projects.Related websites: https://www.medchemexpress.com
