Product Name :
WHI-P258
Description:
WHI-P258 is a Janus kinase 3 inhibitor. WHI-P131 may provide the basis for the design of new treatment strategies against acute lymphoblastic leukemia, the most common form of childhood cancer.
CAS:
21561-09-1
Molecular Weight:
281.31
Formula:
C16H15N3O2
Chemical Name:
6,7-Dimethoxy-N-phenylquinazolin-4-amine
Smiles :
COC1=CC2=NC=NC(NC3C=CC=CC=3)=C2C=C1OC
InChiKey:
MJKCGAHOCZLYDG-UHFFFAOYSA-N
InChi :
InChI=1S/C16H15N3O2/c1-20-14-8-12-13(9-15(14)21-2)17-10-18-16(12)19-11-6-4-3-5-7-11/h3-10H,1-2H3,(H,17,18,19)
Purity:
≥98% (or refer to the Certificate of Analysis)
Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.{{Dehydroabietic acid} web|{Dehydroabietic acid} Cell Cycle/DNA Damage|{Dehydroabietic acid} Protocol|{Dehydroabietic acid} In Vitro|{Dehydroabietic acid} custom synthesis|{Dehydroabietic acid} Epigenetic Reader Domain}
Shelf Life:
≥12 months if stored properly.
Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.
Additional information:
WHI-P258 is a Janus kinase 3 inhibitor.{{Teropavimab} MedChemExpress|{Teropavimab} Anti-infection|{Teropavimab} TGF-beta/Smad|{Teropavimab} Protocol|{Teropavimab} Purity|{Teropavimab} supplier} WHI-P131 may provide the basis for the design of new treatment strategies against acute lymphoblastic leukemia, the most common form of childhood cancer.PMID:35116795 |Product information|CAS Number: 21561-09-1|Molecular Weight: 281.31|Formula: C16H15N3O2|Synonym:|WHI-P-258|WHI-P258|WHI-P 258|WHIP 258|Chemical Name: 6,7-Dimethoxy-N-phenylquinazolin-4-amine|Smiles: COC1=CC2=NC=NC(NC3C=CC=CC=3)=C2C=C1OC|InChiKey: MJKCGAHOCZLYDG-UHFFFAOYSA-N|InChi: InChI=1S/C16H15N3O2/c1-20-14-8-12-13(9-15(14)21-2)17-10-18-16(12)19-11-6-4-3-5-7-11/h3-10H,1-2H3,(H,17,18,19)|Technical Data|Appearance: Solid Power.|Purity: ≥98% (or refer to the Certificate of Analysis)|Solubility: Soluble in DMSO|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.|Shelf Life: ≥12 months if stored properly.|Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.|Drug Formulation: To be determined.|HS Tariff Code: 382200|References:|Sudbeck EA, Liu XP, Narla RK, Mahajan S, Ghosh S, Mao C, Uckun FM. Structure-based design of specific inhibitors of Janus kinase 3 as apoptosis-inducing antileukemic agents. Clin Cancer Res. 1999 Jun;5(6):1569-82. PubMed PMID: 10389946.Products are for research use only. Not for human use.|
