Product Name :
LM22A-4
Description:
LM22A-4 (LM 22A4) is a specific agonist of tyrosine kinase receptor B (TrkB) that reduces the development of tissue injury associated with spinal cord trauma.
CAS:
37988-18-4
Molecular Weight:
339.34
Formula:
C15H21N3O6
Chemical Name:
N1,N3,N5-tris(2-hydroxyethyl)benzene-1,3,5-tricarboxamide
Smiles :
OCCNC(=O)C1C=C(C=C(C=1)C(=O)NCCO)C(=O)NCCO
InChiKey:
RGWJKANXFYJKHN-UHFFFAOYSA-N
InChi :
InChI=1S/C15H21N3O6/c19-4-1-16-13(22)10-7-11(14(23)17-2-5-20)9-12(8-10)15(24)18-3-6-21/h7-9,19-21H,1-6H2,(H,16,22)(H,17,23)(H,18,24)
Purity:
≥98% (or refer to the Certificate of Analysis)
Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life:
≥12 months if stored properly.
Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.
Additional information:
LM22A-4 (LM 22A4) is a specific agonist of tyrosine kinase receptor B (TrkB) that reduces the development of tissue injury associated with spinal cord trauma.|Product information|CAS Number: 37988-18-4|Molecular Weight: 339.34|Formula: C15H21N3O6|Chemical Name: N1,N3,N5-tris(2-hydroxyethyl)benzene-1,3,5-tricarboxamide|Smiles: OCCNC(=O)C1C=C(C=C(C=1)C(=O)NCCO)C(=O)NCCO|InChiKey: RGWJKANXFYJKHN-UHFFFAOYSA-N|InChi: InChI=1S/C15H21N3O6/c19-4-1-16-13(22)10-7-11(14(23)17-2-5-20)9-12(8-10)15(24)18-3-6-21/h7-9,19-21H,1-6H2,(H,16,22)(H,17,23)(H,18,24)|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Solubility: DMSO 68 mg/mL (200.{{SAH} site|{SAH} Metabolic Enzyme/Protease|{SAH} Technical Information|{SAH} In Vivo|{SAH} custom synthesis|{SAH} Epigenetics} 39 mM) Water 68 mg/mL (200.{{Lamivudine} site|{Lamivudine} HBV|{Lamivudine} Protocol|{Lamivudine} References|{Lamivudine} custom synthesis|{Lamivudine} Autophagy} 39 mM) Ethanol 3 mg/mL (8.PMID:23773119 84 mM)|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.|Shelf Life: ≥12 months if stored properly.|Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.|Drug Formulation: To be determined|HS Tariff Code: 382200|References:|Yu G, et al. Protective effects of LM22A-4 on injured spinal cord nerves. Int J Clin Exp Pathol. 2015 Jun 1;8(6):6526-32. eCollection 2015.Kajiya M, et al. BDNF mimetic compound LM22A-4 regulates cementoblast differentiation via the TrkB-ERK/Akt signaling cascade. Int Immunopharmacol. 2014 Apr;19(2):245-52.Products are for research use only. Not for human use.|
