Product Name :
HS80
Description:
HS-80 is an enantiomer of Fasnall, which is a selective fatty acid synthase (FASN) inhibitor. HS-80 is able to inhibit the incorporation of tritiated acetate into lipids with an IC50 of 7.13 μM.
CAS:
2138838-57-8
Molecular Weight:
338.47
Formula:
C19H22N4S
Chemical Name:
(3S)-1-benzyl-N-{5,6-dimethylthieno[2,3-d]pyrimidin-4-yl}pyrrolidin-3-amine
Smiles :
CC1C2=C(N[C@@H]3CN(CC4C=CC=CC=4)CC3)N=CN=C2SC=1C
InChiKey:
VSXRMURGJRAOCU-INIZCTEOSA-N
InChi :
InChI=1S/C19H22N4S/c1-13-14(2)24-19-17(13)18(20-12-21-19)22-16-8-9-23(11-16)10-15-6-4-3-5-7-15/h3-7,12,16H,8-11H2,1-2H3,(H,20,21,22)/t16-/m0/s1
Purity:
≥98% (or refer to the Certificate of Analysis)
Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.{{Belantamab} web|{Belantamab} TNF Receptor|{Belantamab} Protocol|{Belantamab} Data Sheet|{Belantamab} supplier|{Belantamab} Cancer}
Shelf Life:
≥12 months if stored properly.
Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.
Additional information:
HS-80 is an enantiomer of Fasnall, which is a selective fatty acid synthase (FASN) inhibitor.{{Tisotumab vedotin} web|{Tisotumab vedotin} Antibody-Drug Conjugates (ADCs)|{Tisotumab vedotin} Purity & Documentation|{Tisotumab vedotin} Purity|{Tisotumab vedotin} custom synthesis|{Tisotumab vedotin} Autophagy} HS-80 is able to inhibit the incorporation of tritiated acetate into lipids with an IC50 of 7.13 μM.|Product information|CAS Number: 2138838-57-8|Molecular Weight: 338.PMID:32803353 47|Formula: C19H22N4S|Chemical Name: (3S)-1-benzyl-N-{5,6-dimethylthieno[2,3-d]pyrimidin-4-yl}pyrrolidin-3-amine|Smiles: CC1C2=C(N[C@@H]3CN(CC4C=CC=CC=4)CC3)N=CN=C2SC=1C|InChiKey: VSXRMURGJRAOCU-INIZCTEOSA-N|InChi: InChI=1S/C19H22N4S/c1-13-14(2)24-19-17(13)18(20-12-21-19)22-16-8-9-23(11-16)10-15-6-4-3-5-7-15/h3-7,12,16H,8-11H2,1-2H3,(H,20,21,22)/t16-/m0/s1|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.|Shelf Life: ≥12 months if stored properly.|Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.|Drug Formulation: To be determined|HS Tariff Code: 382200|How to use|In Vitro:|Fasnall, a thiophenopyrimidine selectively targeting FASN through its co-factor binding sites. Fasnall has anti-proliferative activity and induces apoptosis in breast cancer cells.|Products are for research use only. Not for human use.|
