Product Name: DUSP3 antibody [N1C3]
Applications: IHC-P, WB
Predicted Target Size: 20 kDa (note)
Positive Controls: 293T , A431 , HeLa , HepG2 , mouse stomach
Form Supplied: Liquid
Concentration: 0.58 mg/ml (Please refer to the vial label for the specific concentration)
Purification: Purified by antigen-affinity chromatography.
Full Name: dual specificity phosphatase 3
Background: The protein encoded by this gene is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which are associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. This gene maps in a region that contains the BRCA1 locus which confers susceptibility to breast and ovarian cancer. Although DUSP3 is expressed in both breast and ovarian tissues, mutation screening in breast cancer pedigrees and in sporadic tumors was negative, leading to the conclusion that this gene is not BRCA1. [provided by RefSeq]
Synonyms: VHR antibody, DUSP3 antibody, vaccinia H1-related phosphatase antibody, serine/threonine specific protein phosphatase antibody, dual specificity protein phosphatase 3 antibody, dual specificity protein phosphatase VHR antibody, vaccinia virus phosphatase VH1-related antibody, dual specificity phosphatase 3 antibody
Cellular Localization:
CAS NO: 1151830
Product: Teneligliptin (hydrobromide)
Host: Rabbit
Clonality: Polyclonal
Isotype: IgG
Immunogen: Full length human DUSP3 Recombinant protein.
Antigen Species: Human
Species Reactivity: Human, Mouse
Conjugation: Unconjugated
Storage Buffer: 0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
Storage Instruction: Keep as concentrated solution. Aliquot and store at -20ÂșC or below. Avoid multiple freeze-thaw cycles.
Notes: For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Specificity:
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/27605709?dopt=Abstract
