Product Name: DUSP8 antibody [N1], N-term
Applications: ICC/IF, WB
Predicted Target Size: 66 kDa (note)
Positive Controls: Raji
Form Supplied: Liquid
Concentration: 0.72 mg/ml (Please refer to the vial label for the specific concentration)
Purification: Purified by antigen-affinity chromatography.
Full Name: dual specificity phosphatase 8
Background: The protein encoded by this gene is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which is associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. This gene product inactivates SAPK/JNK and p38, is expressed predominantly in the adult brain, heart, and skeletal muscle, is localized in the cytoplasm, and is induced by nerve growth factor and insulin. An intronless pseudogene for DUSP8 is present on chromosome 10q11.2. [provided by RefSeq]
Synonyms: C11orf81 antibody, FLJ42476 antibody, FLJ42958 antibody, HB5 antibody, HVH-5 antibody, HVH8 antibody, DUSP8 antibody, serine/threonine specific protein phosphatase antibody, “H1 phosphatase, vaccinia virus homolog antibody”, dual specificity protein phosphatase 8 antibody, dual specificity protein phosphatase hVH-5 antibody, dual specificity phosphatase 8 antibody
Cellular Localization:
CAS NO: 122111-03-9
Product: Metoclopramide
Host: Rabbit
Clonality: Polyclonal
Isotype: IgG
Immunogen: Carrier-protein conjugated synthetic peptide encompassing a sequence within the N-terminus region of human DUSP8. The exact sequence is proprietary.
Antigen Species: Human
Species Reactivity: Human
Conjugation: Unconjugated
Storage Buffer: 0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
Storage Instruction: Keep as concentrated solution. Aliquot and store at -20ÂșC or below. Avoid multiple freeze-thaw cycles.
Notes: For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Specificity:
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/27740908?dopt=Abstract
