Product Name: Dynamin 2 antibody [N1N3]
Applications: ICC/IF, IHC-P, WB
Predicted Target Size: 98 kDa (note) (6)
Positive Controls: A549 , HeLa , mouse brain , PC-12 , Rat-2 , rat brain
Form Supplied: Liquid
Concentration: 0.9 mg/ml (Please refer to the vial label for the specific concentration)
Purification: Purified by antigen-affinity chromatography.
Full Name: dynamin 2
Background: Dynamins represent one of the subfamilies of GTP-binding proteins. These proteins share considerable sequence similarity over the N-terminal portion of the molecule, which contains the GTPase domain. Dynamins are associated with microtubules. They have been implicated in cell processes such as endocytosis and cell motility, and in alterations of the membrane that accompany certain activities such as bone resorption by osteoclasts. Dynamins bind many proteins that bind actin and other cytoskeletal proteins. Dynamins can also self-assemble, a process that stimulates GTPase activity. Four alternatively spliced transcripts encoding different proteins have been described. Additional alternatively spliced transcripts may exist, but their full-length nature has not been determined. [provided by RefSeq]
Synonyms: CMT2M antibody, CMTDI1 antibody, CMTDIB antibody, DI-CMTB antibody, DYN2 antibody, DYNII antibody, DNM2 antibody, dynamin II antibody, dynamin-2 antibody, dynamin 2 antibody
Cellular Localization: Cytoplasm , cytoskeleton , Cell junction , synapse , postsynaptic cell membrane , postsynaptic density
CAS NO: 117704-25-3
Product: UK-5099
Host: Rabbit
Clonality: Polyclonal
Isotype: IgG
Immunogen: Recombinant protein encompassing a sequence within the center region of human Dynamin 2. The exact sequence is proprietary.
Antigen Species: Human
Species Reactivity: Human, Mouse, Rat
Conjugation: Unconjugated
Storage Buffer: 0.1M Tris, 0.1M Glycine, 20% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
Storage Instruction: Keep as concentrated solution. Aliquot and store at -20ÂșC or below. Avoid multiple freeze-thaw cycles.
Notes: For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Specificity:
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/26395144?dopt=Abstract
