Product Name: Dynein Intermediate chain antibody [70.1]
Applications: EM, ELISA, ICC/IF, IP, WB
Predicted Target Size:
Positive Controls: chicken brain
Form Supplied: Liquid
Concentration:
Purification: Unpurified
Full Name: dynein, axonemal, intermediate chain 1
Background: Eukaryotic cells rely on actin and microtubule-based protein “”motors”” to generate intracellular movements (4). These protein “”motors”” contain specialized domains that hydrolyze ATP to produce force and movement along a cytoskeletal polymer (actin in the case of myosin family and microtubules in the case of the kinesin family and dyneins). Dynein has been implicated in cytoplasmic motile functions, including chromosomal movement, retrograde organelle and axonal transport, the endocytic pathway, and the organization of the Golgi apparatus. In all cell types, dynein has the same basic structures and is composed of two or three distinct heavy chains (~450 kD), three intermediate chains (70-125 kD), and at least four light chains (15-25 kD) (5).
Synonyms: DNAI1, ICS, MGC26204, 242650, Dynein Intermediate chain, PCD, Q9UI46, CILD1, 27019
Cellular Localization:
CAS NO: 141625-93-6
Product: Dabigatran (ethyl ester)
Host: Mouse
Clonality: Monoclonal
Isotype: IgM
Immunogen: cytoplasmic dynein from chicken embryo brain
Antigen Species: Chicken
Species Reactivity: Human, Chicken, Rat, Hamster, Indian Muntjac, Marsupials, frog
Conjugation: Unconjugated
Storage Buffer: Ascites, 15 mM sodium azide
Storage Instruction: Keep as concentrated solution. For short-term storage, store at 4° C (up to 10 days). For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Notes: For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Specificity:
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/26183180?dopt=Abstract
