Product Name: E2F1 antibody [6B5]
Applications: IP, WB
Predicted Target Size:
Positive Controls: MCF-7
Form Supplied: Liquid
Concentration: 2.29 mg/ml (Please refer to the vial label for the specific concentration)
Purification: Protein G purified
Full Name: E2F transcription factor 1
Background: E2F-1-6B5 recognizes E2F-1 that was identified as a cellular protein with DNA binding activity associated with the adenovirus E2 gene promoter. The original member of the E2F family of transcription factors, now consisting of five, was identified through its association with the retinoblastoma protein, which controls its activity. E2F-1 is cell cycle regulated with very low levels in early G1 then increasing levels as cells move from G1 to S with highest levels of protein at the G1/S boundary, which is consistent with its role in S-phase entry.
Synonyms: E2F1, E2F-1, Q01094, 189971, 1869, RBP3, RBBP3, RBAP1, E2F 1
Cellular Localization: Nuclear
CAS NO: 821794-92-7
Product: PF-04447943
Host: Mouse
Clonality: Monoclonal
Isotype: IgG1
Immunogen: The region encoding the DP-1 binding site (amino acids 223-332) of E2F-1 expressed in E. coli.
Antigen Species: Human
Species Reactivity: Human
Conjugation: Unconjugated
Storage Buffer: PBS
Storage Instruction: Keep as concentrated solution. Store at 4°C short term. For extended storage aliquot and store at -20°C or below. Avoid freeze-thaw cycles.
Notes: For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Specificity: This antibody recognizes E2F-1 that was identified as a cellular protein with DNA binding activity associated with the adenovirus E2 gene promoter.
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/25875288?dopt=Abstract
