Product Name: E2F1 antibody [KH95]
Applications: IHC, IHC-Fr, IHC-P
Predicted Target Size:
Positive Controls: Tonsil and Breast carcinoma.
Form Supplied: Liquid
Concentration:
Purification: IgG fraction
Full Name: E2F transcription factor 1
Background: E2Fs are DNA binding proteins, which associate with negative regulators, such as the retinoblastoma p107 protein, resulting in an altered rate of gene transcription. E2F 1 is proposed to be involved in several cellular processes that range from tumor suppressor, cell progression and oncogenesis. E2F 1 overexpression can also drive cells into apoptosis.
Synonyms: E2F1, E2F-1, Q01094, 189971, 1869, RBP3, RBBP3, E2F 1
Cellular Localization: Nuclear
CAS NO: 5786-21-0
Product: Bitopertin
Host: Mouse
Clonality: Monoclonal
Isotype: IgG2a
Immunogen: Recombinant full length protein (Human).
Antigen Species: Human
Species Reactivity: Human, Mouse
Conjugation: Unconjugated
Storage Buffer: PBS with sodium azide
Storage Instruction: Keep as concentrated solution, aliquot and store at 4°C. Do not freeze.
Notes: For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Specificity: Protein of 60 kDa.
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/26180204?dopt=Abstract