Product Name: E2F3 antibody
Applications: ELISA, ICC/IF, IHC-P, WB
Predicted Target Size:
Positive Controls:
Form Supplied: Liquid
Concentration: 1 mg/ml (Please refer to the vial label for the specific concentration)
Purification: Affinity chromatography purified via peptide column.
Full Name: E2F transcription factor 3
Background: This gene encodes a member of a small family of transcription factors that function through binding of DP interaction partner proteins. The encoded protein recognizes a specific sequence motif in DNA and interacts directly with the retinoblastoma protein (pRB) to regulate the expression of genes involved in the cell cycle. Altered copy number and activity of this gene have been observed in a number of human cancers. There are pseudogenes for this gene on chromosomes 2 and 17. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2013]
Synonyms: E2F-3 Antibody , E2F transcription factor 3 Antibody
Cellular Localization:
CAS NO: 168273-06-1
Product: SB-674042
Host: Rabbit
Clonality: Polyclonal
Isotype: IgG
Immunogen: E2F3 antibody was raised against a 15 amino acid peptide near the center of human E2F3.
Antigen Species: Human
Species Reactivity: Human
Conjugation: Unconjugated
Storage Buffer: PBS containing 0.02% sodium azide.
Storage Instruction: Be stored at 4oC for three months and -20oC, stable for up to one year.
Notes: For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Specificity: E2F3 antibody is human reactive. At least three isoforms of E2F3 are known to exist; this antibody will detect only the largest isoform. This antibody is predicted to not cross-react with other members of the E2F transcription factor family.
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/25448886?dopt=Abstract
