Product Name: EB1 antibody [N1C3]
Applications: WB
Predicted Target Size: 30 kDa (note)
Positive Controls: 293T , A431 , Jurkat , Raji
Form Supplied: Liquid
Concentration: 0.87 mg/ml (Please refer to the vial label for the specific concentration)
Purification: Purified by antigen-affinity chromatography.
Full Name: microtubule-associated protein, RP/EB family, member 1
Background: The protein encoded by this gene was first identified by its binding to the APC protein which is often mutated in familial and sporadic forms of colorectal cancer. This protein localizes to microtubules, especially the growing ends, in interphase cells. During mitosis, the protein is associated with the centrosomes and spindle microtubules. The protein also associates with components of the dynactin complex and the intermediate chain of cytoplasmic dynein. Because of these associations, it is thought that this protein is involved in the regulation of microtubule structures and chromosome stability. This gene is a member of the RP/EB family. [provided by RefSeq]
Synonyms: EB1 antibody, MGC117374 antibody, MGC129946 antibody, MAPRE1 antibody, microtubule-associated protein RP/EB family member 1 antibody, APC-binding protein EB1 antibody, end-binding protein 1 antibody, adenomatous polyposis coli-binding protein EB1 antibody, “microtubule-associated protein, RP/EB family, member 1 antibody”
Cellular Localization: Cytoplasm
CAS NO: 425386-60-3
Product: Diphenmanil (methylsulfate)
Host: Rabbit
Clonality: Polyclonal
Isotype: IgG
Immunogen: Recombinant protein encompassing a sequence within the center region of human EB1. The exact sequence is proprietary.
Antigen Species: Human
Species Reactivity: Human
Conjugation: Unconjugated
Storage Buffer: 0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
Storage Instruction: Keep as concentrated solution. Aliquot and store at -20ÂșC or below. Avoid multiple freeze-thaw cycles.
Notes: For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Specificity:
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/25189772?dopt=Abstract
