Product Name: E-Cadherin antibody [67A4] (FITC)
Applications: FACS
Predicted Target Size:
Positive Controls:
Form Supplied: Liquid
Concentration:
Purification:
Full Name: cadherin 1, type 1, E-cadherin (epithelial)
Background: CD324 / E-cadherin is an epithelial cell surface molecule, which provides calcium-dependent homophilic interactions with E-cadherin of another cell. These intaractions take part in morphogenetic programs controlling the maintenance of the structural and functional integrity of epithelia and affect invasive potential of epithelial neoplasms. CD324 / E-cadherin is implicated in cell growth and differentiation, cell recognition, and sorting during developmental morphogenesis, as well as in aggregation-dependent cell survival. CD324 / E-cadherin-mediated cell adhesion system is highly regulated from inside the cell by a number of intracellular signaling pathways.Entrez Gene (human): 16q22.1
Synonyms: Arc-1, CDHE, ECAD, LCAM, UVO, E-Cadherin
Cellular Localization:
CAS NO: 956958-53-5
Product: Calcifediol (monohydrate)
Host: Mouse
Clonality: Monoclonal
Isotype: IgG1
Immunogen: T-47D cells
Antigen Species: Human
Species Reactivity: Human
Conjugation: FITC
Storage Buffer: The reagent is provided in stabilizing phosphate buffered saline (PBS) solution containing 15mM sodium azide.
Storage Instruction: Store in the dark at 2-8°C. Do not freeze. Avoid prolonged exposure to light.
Notes: For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Specificity: The mouse monoclonal antibody 67A4 recognizes CD324 / E-cadherin, an approximately 100 kDa epithelial cell adhesion molecule, whose detection is important for determination of invasive potential of epithelial neoplasms.
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/24496626?dopt=Abstract
