Product Name: EDG1 antibody
Applications: IHC-P, WB
Predicted Target Size:
Positive Controls: Heart, Vessel
Form Supplied: Liquid
Concentration: 1 mg/ml (Please refer to the vial label for the specific concentration)
Purification: Affinity purified with antigen
Full Name: sphingosine-1-phosphate receptor 1
Background: EDG1, a Lysophospholipid/Lysosphingolipid Receptor, binds sphingosine-1-phosphate and may control cell proliferation, survival, and suppression of apoptosis. Overexpression of EDG-1 leads to increased cell-cell aggregation and overexpression of cadherins. EDG-1 transcripts have been reported to be present in embryonic and adult brain, lung alveolar macrophages, vascular smooth muscle cells, endothelial cells, fibroblasts, melanocytes, and TAg-Jurkat T cells, but to be absent from breast cancer cell lines. ESTs have been isolated from brain, breast, heart, heart/melanocyte/uterus, kidney, liver, liver/spleen, lung, nerve, placenta, prostate, tonsil, uterus, and vessel libraries.
Synonyms: Edg1, lpB1, AI849002, IpB1, S1P1, 13609
Cellular Localization:
CAS NO: 625115-55-1
Product: Cevimeline (hydrochloride hemihydrate)
Host: Rabbit
Clonality: Polyclonal
Isotype: IgG
Immunogen: Synthetic peptide (KLH conjugated) – Immunogen sequence information is commercially sensitive. Peptide sequence identity/similarity to Mouse: 93/100%. Rat: 93/100%.
Antigen Species: Human
Species Reactivity: Human
Conjugation: Unconjugated
Storage Buffer: Phosphate-buffered saline, pH 7.4, containing 0.1% sodium azide
Storage Instruction: Keep as concentrated solution. Store at 4ºC short term. For extended storage aliquot and store at -20ºC or below. Avoid freeze-thaw cycles.
Notes: For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Specificity:
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/25100656?dopt=Abstract
