Product Name: EFCAB4A antibody
Applications: ELISA, WB
Predicted Target Size:
Positive Controls: Blocking Peptide:Cat.No. GTX85143-PEP – EFCAB4A PeptideLysates:Cat. No. GTX27917 – Human Lung Tissue Lysate
Form Supplied: Liquid
Concentration:
Purification: Affinity chromatography purified via peptide column
Full Name: EF-hand calcium binding domain 4A
Background: EFCAB4A, also known as Calcium release-activated calcium channel regulator 2B, is a novel Ca2+-binding EF-hand protein that is thought to play a key role in store-operated Ca2+ entry in T-cells by regulating CRAC channel activation, but the detailed function is still under investigation. It is likely to play a similar role as the related protein EFCAB4B, which acts as a cytoplasmic calcium-sensor that forms a complex with ORAI1 and STIM1 at the junctional regions between the plasma membrane and the endoplasmic reticulum upon low Ca2+ concentration.
Synonyms: EFhand calcium binding domain4A, EFCAB4A, Calcium release-activated calcium channel regulator 2, Calcium releaseactivated calcium channel regulator2, CRACR2B, Calcium releaseactivated calcium channel regulator 2, EFhand calcium binding domain 4A, EF-hand calcium binding domain 4A
Cellular Localization:
CAS NO: 1245526-82-2
Product: RI-1
Host: Rabbit
Clonality: Polyclonal
Isotype:
Immunogen:
Antigen Species:
Species Reactivity: Human, Mouse, Rat
Conjugation: Unconjugated
Storage Buffer: PBS containing 0.02% sodium azide
Storage Instruction: Keep as concentrated solution. Aliquot and store at -20ÂșC or below. Avoid multiple freeze-thaw cycles.
Notes: For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Specificity: This antibody is specific for EFCAB4A
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/23966833?dopt=Abstract
