Product Name: EGFR (phospho Ser1047) antibody
Applications: WB
Predicted Target Size:
Positive Controls:
Form Supplied: Liquid
Concentration:
Purification: The antibody was purified by immunogen affinity chromatography.
Full Name: epidermal growth factor receptor
Background: The protein encoded by this gene is a transmembrane glycoprotein that is a member of the protein kinase superfamily. This protein is a receptor for members of the epidermal growth factor family. EGFR is a cell surface protein that binds to epidermal growth factor. Binding of the protein to a ligand induces receptor dimerization and tyrosine autophosphorylation and leads to cell proliferation. Mutations in this gene are associated with lung cancer. Multiple alternatively spliced transcript variants that encode different protein isoforms have been found for this gene. [provided by RefSeq, Jul 2010]
Synonyms: HER1 Antibody , mENA Antibody , epidermal growth factor receptor Antibody , PIG61 Antibody , NISBD2 Antibody , EGFR Antibody , ERBB1 Antibody , ERBB Antibody
Cellular Localization:
CAS NO: 269055-15-4
Product: Quetiapine (fumarate)
Host: Rabbit
Clonality: Polyclonal
Isotype: IgG
Immunogen: KLH-conjugated synthetic peptide encompassing a sequence within the C-term region of human EGFR. The exact sequence is proprietary.
Antigen Species: Human
Species Reactivity: Human, Mouse, Rat
Conjugation: Unconjugated
Storage Buffer: Liquid in 0.42% Potassium phosphate; 0.87% Sodium chloride; pH 7.3; 30% glycerol; and 0.01% sodium azide.
Storage Instruction: Shipped at 4 °C. Upon delivery aliquot and store at -20 °C for one year. Avoid freeze/thaw cycles.
Notes: For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Specificity: The full-length EGFR includes the 24 aa signal peptide that is cleaved during EGFR maturation. The Ser1047 of mature EGFR is equivalent to Ser1071 of uncleaved EGFR.
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/24075965?dopt=Abstract
