Product Name: EGFR (phospho Tyr1045) antibody [11C2]
Applications: ELISA, WB
Predicted Target Size:
Positive Controls:
Form Supplied: Liquid
Concentration:
Purification: Purified IgG
Full Name: epidermal growth factor receptor
Background: The protein encoded by this gene is a transmembrane glycoprotein that is a member of the protein kinase superfamily. This protein is a receptor for members of the epidermal growth factor family. EGFR is a cell surface protein that binds to epidermal growth factor. Binding of the protein to a ligand induces receptor dimerization and tyrosine autophosphorylation and leads to cell proliferation. Mutations in this gene are associated with lung cancer. Multiple alternatively spliced transcript variants that encode different protein isoforms have been found for this gene. [provided by RefSeq, Jul 2010]
Synonyms: MENA Antibody , HER1 Antibody , ERBB1 Antibody , EGFR Antibody , ERBB Antibody , PIG61 Antibody
Cellular Localization:
CAS NO: 1137608-69-5
Product: IRAK-1-4 Inhibitor I
Host: Mouse
Clonality: Monoclonal
Isotype: IgG1
Immunogen:
Antigen Species:
Species Reactivity: Human
Conjugation: Unconjugated
Storage Buffer:
Storage Instruction: Keep as concentrated solution. Aliquot and store at -20ÂșC or below. Avoid multiple freeze-thaw cycles.
Notes: For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Specificity: The full-length EGFR includes the 24 aa signal peptide that is cleaved during EGFR maturation. The Tyr1045 of mature EGFR is equivalent to Tyr1069 of uncleaved EGFR.
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/24137111?dopt=Abstract
