Product Name: EIF3 beta antibody [N2C3]
Applications: ICC/IF, WB
Predicted Target Size: 37 kDa (note)
Positive Controls: A431 , H1299 , HeLa , HepG2
Form Supplied: Liquid
Concentration: 2 mg/ml (Please refer to the vial label for the specific concentration)
Purification: Affinity purified by Protein A.
Full Name: eukaryotic translation initiation factor 3, subunit I
Background: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S preinitiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of posttermination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation.
Synonyms: EIF3S2 antibody, PRO2242 antibody, TRIP-1 antibody, TRIP1 antibody, eIF3-beta antibody, eIF3-p36 antibody, EIF3I antibody, predicted protein of HQ2242 antibody, TGF-beta receptor-interacting protein 1 antibody, TGFbeta receptor-interacting protein 1 antibody, eukaryotic translation initiation factor 3 subunit I antibody, “eukaryotic translation initiation factor 3, subunit 2 (beta, 36kD) antibody”, “eukaryotic translation initiation factor 3, subunit 2 beta, 36kDa antibody”, eukaryotic translation initiation factor 3 subunit 2 antibody, eIF-3-beta antibody, eIF3 p36 antibody, “eukaryotic translation initiation factor 3, subunit I antibody”
Cellular Localization:
CAS NO: 702675-74-9
Product: Daclatasvir (dihydrochloride)
Host: Rabbit
Clonality: Polyclonal
Isotype: IgG
Immunogen: Recombinant protein encompassing a sequence within the center region of human EIF3 beta. The exact sequence is proprietary.
Antigen Species: Human
Species Reactivity: Human
Conjugation: Unconjugated
Storage Buffer: 1XPBS, 40% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
Storage Instruction: Keep as concentrated solution. Aliquot and store at -20ÂșC or below. Avoid multiple freeze-thaw cycles.
Notes: For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Specificity:
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/21466691?dopt=Abstract
