Product Name: EIF3F antibody [N1C3]
Applications: ICC/IF, IHC-P, WB
Predicted Target Size: 38 kDa (note)
Positive Controls: A431
Form Supplied: Liquid
Concentration: 0.39 mg/ml (Please refer to the vial label for the specific concentration)
Purification: Purified by antigen-affinity chromatography.
Full Name: eukaryotic translation initiation factor 3, subunit F
Background: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S preinitiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of posttermination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation.
Synonyms: EIF3S5 antibody, eIF3-p47 antibody, EIF3F antibody, “eukaryotic translation initiation factor 3, subunit 5 epsilon, 47kDa antibody”, eIF3-epsilon antibody, “eukaryotic translation initiation factor 3, subunit 5 (epsilon, 47kD) antibody”, eukaryotic translation initiation factor 3 subunit F antibody, eIF-3-epsilon antibody, “eukaryotic translation initiation factor 3, subunit F antibody”
Cellular Localization: Cytoplasm
CAS NO: 341001-38-5
Product: YM-201636
Host: Rabbit
Clonality: Polyclonal
Isotype: IgG
Immunogen: Recombinant protein encompassing a sequence within the center region of human EIF3F. The exact sequence is proprietary.
Antigen Species: Human
Species Reactivity: Human, Mouse
Conjugation: Unconjugated
Storage Buffer: 1XPBS, 1% BSA, 20% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
Storage Instruction: Keep as concentrated solution. Aliquot and store at -20ÂșC or below. Avoid multiple freeze-thaw cycles.
Notes: For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Specificity:
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/21533269?dopt=Abstract
