Product Name: eIF3H / EIF3S3 antibody [N2C3]
Applications: WB
Predicted Target Size: 40 kDa (note)
Positive Controls: 293T , A431 , H1299 , HeLaS3 , HepG2 , Molt-4 , Raji
Form Supplied: Liquid
Concentration: 0.87 mg/ml (Please refer to the vial label for the specific concentration)
Purification: Purified by antigen-affinity chromatography.
Full Name: eukaryotic translation initiation factor 3, subunit H
Background: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S preinitiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of posttermination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation.
Synonyms: EIF3S3 antibody, MGC102958 antibody, eIF3-gamma antibody, eIF3-p40 antibody, EIF3H antibody, eukaryotic translation initiation factor 3 subunit 3 antibody, eIF-3-gamma antibody, eukaryotic translation initiation factor 3 subunit H antibody, “eukaryotic translation initiation factor 3, subunit 3 gamma, 40kDa antibody”, “eukaryotic translation initiation factor 3, subunit 3 (gamma, 40kD) antibody”, “eukaryotic translation initiation factor 3, subunit 2 (beta, 36kD) antibody”, eIF3 p40 subunit antibody, “eukaryotic translation initiation factor 3, subunit H antibody”
Cellular Localization: Cytoplasm
CAS NO: 1088965-37-0
Product: PKI-402
Host: Rabbit
Clonality: Polyclonal
Isotype: IgG
Immunogen: Recombinant protein encompassing a sequence within the center region of human EIF3 gamma. The exact sequence is proprietary.
Antigen Species: Human
Species Reactivity: Human
Conjugation: Unconjugated
Storage Buffer: 0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
Storage Instruction: Keep as concentrated solution. Aliquot and store at -20oC or below. Avoid multiple freeze-thaw cycles.
Notes: For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Specificity:
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/21460635?dopt=Abstract
