Product Name: eIF4G (phospho Ser1231) antibody
Applications: IHC, WB
Predicted Target Size:
Positive Controls:
Form Supplied: Liquid
Concentration: 1 mg/ml (Please refer to the vial label for the specific concentration)
Purification: Affinity purified with antigen
Full Name: eukaryotic translation initiation factor 4 gamma, 1
Background: The protein encoded by this gene is a component of the multi-subunit protein complex EIF4F. This complex facilitates the recruitment of mRNA to the ribosome, which is a rate-limiting step during the initiation phase of protein synthesis. The recognition of the mRNA cap and the ATP-dependent unwinding of 5-terminal secondary structure is catalyzed by factors in this complex. The subunit encoded by this gene is a large scaffolding protein that contains binding sites for other members of the EIF4F complex. A domain at its N-terminus can also interact with the poly(A)-binding protein, which may mediate the circularization of mRNA during translation. Alternative splicing results in multiple transcript variants, some of which are derived from alternative promoter usage. [provided by RefSeq, Aug 2010]
Synonyms: EIF4G1 Antibody , phospho eIF4G S1231 Antibody , phospho eIF4G Ser1231 Antibody , EIF4F Antibody , eIF4G phospho Ser1231 Antibody , eIF4G (pSer1231) Antibody , Phospho eIF4G (pSer1231) Antibody , eIF4G (Phospho S1231) Antibody , eIF4G (Phospho Ser1231) Antibody , eIF4G (pS1231) Antibody , phospho eIF4G Antibody , eIF4G phospho S1231 Antibody , P220 Antibody , eIF4G S1231 phospho Antibody , EIF4GI Antibody , phospho S1231 eIF4G Antibody , phospho Ser1231 eIF4G Antibody , Phospho eIF4G (Ser1231) Antibody , EIF-4G1 Antibody , EIF4G Antibody , eIF4G phospho Antibody , Phospho eIF4G (pS1231) Antibody , eIF4G Ser1231 phospho Antibody , PARK18 Antibody
Cellular Localization: Nuclear, but also found in the cytoplasm in an inactive form complexed to an inhibitor.
CAS NO: 204697-65-4
Product: PIK-93
Host: Rabbit
Clonality: Polyclonal
Isotype: IgG
Immunogen:
Antigen Species: Human
Species Reactivity: Human, Mouse, Rat
Conjugation: Unconjugated
Storage Buffer: PBS (without Mg2+and Ca2+), pH 7.4, 150mM NaCl,0.02% sodium azide and 50% glycerol.
Storage Instruction: Keep as concentrated solution. Aliquot and store at -20ÂșC or below. Avoid multiple freeze-thaw cycles.
Notes: For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Specificity:
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/20203170?dopt=Abstract
