Product Name: ELKS / RAB6IP2 antibody, N-term
Applications: WB
Predicted Target Size:
Positive Controls: The peptide used to product this antibody is available for purchase (Catalog Number:GTX41192-PEP).
Form Supplied: Liquid
Concentration: 0.5 mg/ml (Please refer to the vial label for the specific concentration)
Purification: Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Full Name: ELKS/RAB6-interacting/CAST family member 1
Background: Regulatory subunit of the IKK complex. Probably recruits IkappaBalpha/NFKBIA to the complex. May be involved in the organization of the cytomatrix at the nerve terminals active zone (CAZ) which regulates neurotransmitter release. May be involved in vesicle trafficking at the CAZ. May be involved in Rab-6 regulated endosomes to Golgi transport. The protein is a member of a family of RIM-binding proteins. RIMs are active zone proteins that regulate neurotransmitter release. This gene has been found fused to the receptor-type tyrosine kinase gene RET by gene rearrangement due to the translocation t(10;12)(q11;p13). Five transcript variants encoding different isoforms have been found for this gene.
Synonyms: Rab6interacting protein2, RAB6IP2, ELKS/RAB6interacting/CAST family member 1, KIAA1081, ELKS/RAB6interacting/CAST family member1, RAB6 interacting protein 2, OTTHUMP00000160633, Cast2, Rab6-interacting protein 2, MGC12974, RAB6interacting protein 2, FLJ31750, ELKS, ELKS / RAB6IP2, RAB6 interacting protein2, R
Cellular Localization: Cytoplasmic and membrane associated.
CAS NO: 783355-60-2
Product: Riociguat
Host: Goat
Clonality: Polyclonal
Isotype: IgG
Immunogen: YGSARSVGKVEPS-C
Antigen Species: Human
Species Reactivity: Human
Conjugation: Unconjugated
Storage Buffer: Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
Storage Instruction: Aliquot and store at -20°C. Minimize freezing and thawing.
Notes: For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Specificity: This antibody is specific for ELKS / RAB6IP2.
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/27488962?dopt=Abstract
