Product Name: Elovl6 antibody
Applications: ELISA, IHC, WB
Predicted Target Size:
Positive Controls:
Form Supplied: Liquid
Concentration: 1.0 mg/ml (Please refer to the vial label for the specific concentration)
Purification: Purified by antigen-affinity chromatography.
Full Name: ELOVL fatty acid elongase 6
Background: Lipogenesis is a key event in the energy storage system and is controlled by the transcription factor sterol regulatory element-binding protein (SREBP)-1. Elongation of very long chain fatty acids protein 6 (ELOVL6) is a member of fatty acyl-CoA elongase gene family that converts palmitic to stearic acid and it has been shown to be a target of SREBP-1, playing an important role in de novo synthesis of long-chain saturated and monosaturated fatty acids in conjunction with fatty acid synthase and stearoyl-CoA desaturase. ELOVL6 was predicted to be important for tissue fatty acid composition. Recent studies suggest that inhibition of this elongase could be a new therapeutic approach for ameliorating insulin resistance, diabetes and cardiovascular risks, even in the presence of a continuing state of obesity.
Synonyms: FAE Antibody , LCE Antibody , FACE Antibody , ELOVL6 Antibody
Cellular Localization:
CAS NO: 1415559-43-1
Product: Alvimopan
Host: Rabbit
Clonality: Polyclonal
Isotype: IgG
Immunogen: ELOVL6 Antibody was produced from whole rabbit serum prepared by repeated immunizations with a peptide near the n-terminus of the human ELOVL6.
Antigen Species: Human
Species Reactivity: Human, Mouse, Rat, Bovine
Conjugation: Unconjugated
Storage Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2 and 0.01% (w/v) Sodium Azide
Storage Instruction: Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing.
Notes: For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Specificity:
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/25582703?dopt=Abstract
