Product Name: ELOVL7 antibody
Applications: ELISA, ICC/IF, IHC-P, WB
Predicted Target Size:
Positive Controls: Blocking Peptide:
Form Supplied: Liquid
Concentration:
Purification: Affinity chromatography purified via peptide column
Full Name: ELOVL family member 7, elongation of long chain fatty acids (yeast)
Background: Lipogenesis is a key event in the energy storage system and is controlled by the transcription factor sterol regulatory element-binding protein (SREBP)-1. Elongation of very long chain fatty acids protein 7 (ELOVL7) is a member of fatty acyl-CoA elongase gene family that elongates saturated very-long-chain fatty acids (SVLFA, C20:0-) and has been suggested to be involved in prostate cancer growth through saturated long-chain fatty acid metabolism. The metabolic pathways of long-chain fatty acids play an important role in the maintenance of membrane lipid composition and the generation of cell signaling precursor molecules such as eicosanoids and sphingosine-1 phosphate. Overexpression of ELOVL7 results in lipid accumulation in differentiated adipocytes; its expression is regulated by the microRNA miR-219.
Synonyms: Elongation of very long chain fatty acids protein 7, ELOVL7, Elongation of very long chain fatty acids protein7
Cellular Localization:
CAS NO: 201943-63-7
Product: (E)-2-Decenoic acid
Host: Rabbit
Clonality: Polyclonal
Isotype:
Immunogen:
Antigen Species:
Species Reactivity: Human, Mouse
Conjugation: Unconjugated
Storage Buffer: PBS containing 0.02% sodium azide
Storage Instruction: Keep as concentrated solution. Aliquot and store at -20ÂșC or below. Avoid multiple freeze-thaw cycles.
Notes: For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Specificity: This antibody is specific for ELOVL7
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/25055869?dopt=Abstract
