Product Name: EML1 antibody [N1N3]
Applications: WB
Predicted Target Size: 90 kDa (note) (2)
Positive Controls: A549 , HeLa , HepG2 , mouse brain
Form Supplied: Liquid
Concentration: 0.62 mg/ml (Please refer to the vial label for the specific concentration)
Purification: Purified by antigen-affinity chromatography.
Full Name: echinoderm microtubule associated protein like 1
Background: Human echinoderm microtubule-associated protein-like is a strong candidate for the Usher syndrome type 1A gene. Usher syndromes (USHs) are a group of genetic disorders consisting of congenital deafness, retinitis pigmentosa, and vestibular dysfunction of variable onset and severity depending on the genetic type. The disease process in USHs involves the entire brain and is not limited to the posterior fossa or auditory and visual systems. The USHs are catagorized as type I (USH1A, USH1B, USH1C, USH1D, USH1E and USH1F), type II (USH2A and USH2B) and type III (USH3). The type I is the most severe form. Gene loci responsible for these three types are all mapped. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]
Synonyms: ELP79 antibody, EMAP antibody, EMAPL antibody, FLJ45033 antibody, HuEMAP antibody, EML1 antibody, huEMAP-1 antibody, echinoderm microtubule-associated protein-like 1 antibody, EMAP-1 antibody, echinoderm microtubule associated protein like 1 antibody
Cellular Localization: Cytoplasm
CAS NO: 422513-13-1
Product: NXY-059
Host: Rabbit
Clonality: Polyclonal
Isotype: IgG
Immunogen: Recombinant protein encompassing a sequence within the center region of human EML1. The exact sequence is proprietary.
Antigen Species: Human
Species Reactivity: Human, Mouse
Conjugation: Unconjugated
Storage Buffer: 0.1M Tris, 0.1M Glycine, 20% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
Storage Instruction: Keep as concentrated solution. Aliquot and store at -20ÂșC or below. Avoid multiple freeze-thaw cycles.
Notes: For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Specificity:
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/24240238?dopt=Abstract