Product Name: EMR2 antibody [2A1]
Applications: FACS, IHC-Fr, IP, WB
Predicted Target Size:
Positive Controls:
Form Supplied: Liquid
Concentration: 1.0 mg/ml (Please refer to the vial label for the specific concentration)
Purification: Protein A purified
Full Name: adhesion G protein-coupled receptor E2
Background: This gene encodes a member of the class B seven-span transmembrane (TM7) subfamily of G-protein coupled receptors. These proteins are characterized by an extended extracellular region with a variable number of N-terminal epidermal growth factor-like domains coupled to a TM7 domain via a mucin-like spacer domain. The encoded protein is expressed mainly in myeloid cells where it promotes cell-cell adhesion through interaction with chondroitin sulfate chains. This gene is situated in a cluster of related genes on chromosome 19. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Aug 2012]
Synonyms: CD312 Antibody , egf-like module containing, mucin-like, hormone receptor-like 2 Antibody
Cellular Localization:
CAS NO: 1146618-41-8
Product: T0070907
Host: Mouse
Clonality: Monoclonal
Isotype: IgG1
Immunogen: NIH-3T3 cells stably transfected with EMR2 (EGF1-5) cDNA
Antigen Species: Human
Species Reactivity: Human
Conjugation: Unconjugated
Storage Buffer: PBS, 0.09% Sodium Azide
Storage Instruction: Keep as concentrated solution. For short-term storage, store at 4° C (up to 10 days). For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. This product may contain precipitation. Recommend microcentrifugation before use.
Notes: For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Specificity: Clone 2A1 specifically recognizes the stalk region of EMR2.
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/23563706?dopt=Abstract