Product Name: Endothelin A Receptor antibody [C3], C-term
Applications: IHC-P, WB
Predicted Target Size: 49 kDa (note) (3)
Positive Controls: U87-MG , GL261
Form Supplied: Liquid
Concentration: 0.49 mg/ml (Please refer to the vial label for the specific concentration)
Purification: Purified by antigen-affinity chromatography.
Full Name: endothelin receptor type A
Background: This gene encodes the receptor for endothelin-1, a peptide that plays a role in potent and long-lasting vasoconstriction. This receptor associates with guanine-nucleotide-binding (G) proteins, and this coupling activates a phosphatidylinositol-calcium second messenger system. Polymorphisms in this gene have been linked to migraine headache resistance. Alternative splicing results in multiple transcript variants. [provided by RefSeq]
Synonyms: ETA antibody, ETAR antibody, ETRA antibody, EDNRA antibody, “endothelin receptor, ET1-specific type antibody”, endothelin receptor subtype A antibody, endothelin A receptor antibody, endothelin ET-A receptor antibody, G protein-coupled receptor antibody, endothelin-1-specific receptor antibody, hET-AR antibody, endothelin-1 receptor antibody, ET-A antibody, ETA-R antibody, endothelin receptor type A antibody
Cellular Localization: Cell membrane
CAS NO: 857876-30-3
Product: MLN4924
Host: Rabbit
Clonality: Polyclonal
Isotype: IgG
Immunogen: Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human Endothelin A Receptor. The exact sequence is proprietary.
Antigen Species: Human
Species Reactivity: Human, Mouse, Chicken
Conjugation: Unconjugated
Storage Buffer: 0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
Storage Instruction: Keep as concentrated solution. Aliquot and store at -20ÂșC or below. Avoid multiple freeze-thaw cycles.
Notes: For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Specificity:
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/27456541?dopt=Abstract
