Product Name: ENY2 antibody [GT245]
Applications: ICC/IF, IHC-P, WB
Predicted Target Size: 12 kDa (note) (2)
Positive Controls: U87-MG , SK-N-SH , IMR32
Form Supplied: Liquid
Concentration: 1 mg/ml (Please refer to the vial label for the specific concentration)
Purification: Affinity purified by Protein G.
Full Name: enhancer of yellow 2 homolog (Drosophila)
Background: Component of the transcription regulatory histone acetylation (HAT) complex SAGA, a multiprotein complex that activates transcription by remodeling chromatin and mediating histone acetylation and deubiquitination. Within the SAGA complex, participates to a subcomplex that specifically deubiquitinates both histones H2A and H2B. The SAGA complex is recruited to specific gene promoters by activators such as MYC, where it is required for transcription. Required for nuclear receptor-mediated transactivation. May also participate in mRNA export and accurate chromatin positioning in the nucleus by tethering genes to the nuclear periphery.
Synonyms:
Cellular Localization: Nucleus
CAS NO: 1403254-99-8
Product: BMS 777607
Host: Mouse
Clonality: Monoclonal
Isotype: IgG1
Immunogen: Recombinant protein encompassing a sequence within the center region of human ENY2. The exact sequence is proprietary.
Antigen Species: Human
Species Reactivity: Human, Rat
Conjugation: Unconjugated
Storage Buffer: PBS
Storage Instruction: Keep as concentrated solution. Aliquot and store at -20ÂșC or below. Avoid multiple freeze-thaw cycles.
Notes: For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Specificity:
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/26646371?dopt=Abstract
