Product Name: EphA10 antibody
Applications: ELISA, WB
Predicted Target Size:
Positive Controls: Blocking Peptide:Cat.No. GTX85273-PEP – EphA10 PeptideLysates:Cat. No. GTX27902 – 293 Cell Lysate
Form Supplied: Liquid
Concentration:
Purification: Affinity chromatography purified via peptide column
Full Name: EPH receptor A10
Background: Eph receptors, the largest subfamily of receptor tyrosine kinases (RTKs), and their ephrin ligands are important mediators of cell–cell communication regulating cell attachment, shape, and mobility of neuronal and endothelial cells in central nervous system function and in development. Eph receptors can be divided into two subgroups: EphA and EphB. In mammals, the EphA class consists of eight members (EphA 1-7 and 10) that in general bind to ephrin-A members linked to the cell membrane through a glycosylphosphatidylinositol linkage. The EphB class consists of six members (EphB 1-6) that in general bind ephrin-B members that transverse the cell membrane. The Ephrin / EPH signaling pathway networks with the WNT signaling pathway during embryogenesis, tissue regeneration, and carcinogenesis. Recent studies show that Eph/EFN might be relevant in normal B-cell biology and could represent new potential prognostic markers and therapeutic targets for CLL.
Synonyms: EPH receptor A10, EphA10, FLJ16103, Ephrin type-A receptor 10, Ephrin typeA receptor 10, Ephrin typeA receptor10, Ephrin type A receptor 10
Cellular Localization:
CAS NO: 163768-50-1
Product: PHA-848125
Host: Rabbit
Clonality: Polyclonal
Isotype:
Immunogen: immunogen is generated from within aa121-180 of NP_001092909.
Antigen Species:
Species Reactivity: Human, Mouse, Rat
Conjugation: Unconjugated
Storage Buffer: PBS containing 0.02% sodium azide
Storage Instruction: Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Notes: For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Specificity: This antibody is specific for EphA10
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/21611191?dopt=Abstract
