Product Name: EphA3 (phospho Tyr779) / EphA4 (phospho Tyr779) / EphA5 (phospho Tyr833) antibody
Applications: IHC-P
Predicted Target Size:
Positive Controls:
Form Supplied: Liquid
Concentration: 1 mg/ml (Please refer to the vial label for the specific concentration)
Purification: Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide.
Full Name: EPH receptor A3 | EPH receptor A4
Background: This gene belongs to the ephrin receptor subfamily of the protein-tyrosine kinase family. EPH and EPH-related receptors have been implicated in mediating developmental events, particularly in the nervous system. Receptors in the EPH subfamily typically have a single kinase domain and an extracellular region containing a Cys-rich domain and 2 fibronectin type III repeats. The ephrin receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. This gene encodes a protein that binds ephrin-A ligands. Two alternatively spliced transcript variants have been described for this gene. [provided by RefSeq, Jul 2008]
Synonyms: EPHA4 Antibody , HEK4 Antibody , ETK1 Antibody , EK4 Antibody , HEK Antibody , HEK8 Antibody , TYRO1 Antibody , EPH receptor A4 Antibody , EPH receptor A3 Antibody , ETK Antibody , SEK Antibody , TYRO4 Antibody , EPHA3 Antibody
Cellular Localization:
CAS NO: 53123-88-9
Product: Decitabine
Host: Rabbit
Clonality: Polyclonal
Isotype: IgG
Immunogen: Peptide sequence around phosphorylation site of tyrosine 779/833 (E-A-Y(p)-T-T)/(A-A-Y(p)-T-T) derived from Human EPHA3/4/5.
Antigen Species: Human
Species Reactivity: Human
Conjugation: Unconjugated
Storage Buffer: Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Storage Instruction: Store at -20˚C/1 year
Notes: For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Specificity: The antibody detects endogenous levels of EPHA3/4/5 only when phosphorylated at tyrosine 779/833.
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/20028024?dopt=Abstract
