Product Name: Ephrin B3 antibody [C2C3], C-term
Applications: WB
Predicted Target Size: 36 kDa (note)
Positive Controls: 293T , A431 , mouse hippocampus , rat hippocampus
Form Supplied: Liquid
Concentration: 1 mg/ml (Please refer to the vial label for the specific concentration)
Purification: Purified by antigen-affinity chromatography.
Full Name: ephrin-B3
Background: EFNB3, a member of the ephrin gene family, is important in brain development as well as in its maintenance. Moreover, since levels of EFNB3 expression were particularly high in several forebrain subregions compared to other brain subregions, it may play a pivotal role in forebrain function. The EPH and EPH-related receptors comprise the largest subfamily of receptor protein-tyrosine kinases and have been implicated in mediating developmental events, particularly in the nervous system. EPH Receptors typically have a single kinase domain and an extracellular region containing a Cys-rich domain and 2 fibronectin type III repeats. The ephrin ligands and receptors have been named by the Eph Nomenclature Committee (1997). Based on their structures and sequence relationships, ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and the ephrin-B (EFNB) class, which are transmembrane proteins. The Eph family of receptors are similarly divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. [provided by RefSeq]
Synonyms: EFL6 antibody, EPLG8 antibody, LERK8 antibody, EFNB3 antibody, EPH-related receptor transmembrane ligand ELK-L3 antibody, ephrin-B3 antibody, eph-related receptor tyrosine kinase ligand 8 antibody, Ephrin B3 antibody
Cellular Localization: Membrane
CAS NO: 212141-51-0
Product: NVP-BHG712
Host: Rabbit
Clonality: Polyclonal
Isotype: IgG
Immunogen: Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human ephrin-B3. The exact sequence is proprietary.
Antigen Species: Human
Species Reactivity: Human, Mouse, Rat
Conjugation: Unconjugated
Storage Buffer: 0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
Storage Instruction: Keep as concentrated solution. Aliquot and store at -20ÂșC or below. Avoid multiple freeze-thaw cycles.
Notes: For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Specificity:
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/25232125?dopt=Abstract
