Product Name: EPO receptor antibody
Applications: ELISA, IHC-P, WB
Predicted Target Size:
Positive Controls:
Form Supplied: Liquid
Concentration: 0.50 mg/ml (Please refer to the vial label for the specific concentration)
Purification: Affinity purified
Full Name: erythropoietin receptor
Background: This gene encodes the erythropoietin receptor which is a member of the cytokine receptor family. Upon erythropoietin binding, this receptor activates Jak2 tyrosine kinase which activates different intracellular pathways including: Ras/MAP kinase, phosphatidylinositol 3-kinase and STAT transcription factors. The stimulated erythropoietin receptor appears to have a role in erythroid cell survival. Defects in the erythropoietin receptor may produce erythroleukemia and familial erythrocytosis. Dysregulation of this gene may affect the growth of certain tumors. Alternate splicing results in multiple transcript variants.[provided by RefSeq, May 2010]
Synonyms: erythropoietin receptor Antibody , EPO-R Antibody
Cellular Localization:
CAS NO: 60940-34-3
Product: TSU-68
Host: Rabbit
Clonality: Polyclonal
Isotype: IgG
Immunogen:
Antigen Species: Human
Species Reactivity: Human, Mouse, Dog, Rat, Horse, Bovine
Conjugation: Unconjugated
Storage Buffer: 10 mM PBS, pH 7.4 with 10 mg/ml BSA and 0.1% sodium azide
Storage Instruction: Store at 4°C for up to two weeks. For long term storage, aliquot and store at -20°C, avoid freeze/thaw cycles.
Notes: For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Specificity:
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/25951179?dopt=Abstract
