Product Name: EPO receptor antibody [6A33]
Applications: WB
Predicted Target Size:
Positive Controls:
Form Supplied: Liquid
Concentration:
Purification: The IgG fraction of culture supernatant was purified by Protein G affinity chromatography
Full Name: erythropoietin receptor
Background: This gene encodes the erythropoietin receptor which is a member of the cytokine receptor family. Upon erythropoietin binding, this receptor activates Jak2 tyrosine kinase which activates different intracellular pathways including: Ras/MAP kinase, phosphatidylinositol 3-kinase and STAT transcription factors. The stimulated erythropoietin receptor appears to have a role in erythroid cell survival. Defects in the erythropoietin receptor may produce erythroleukemia and familial erythrocytosis. Dysregulation of this gene may affect the growth of certain tumors. Alternate splicing results in multiple transcript variants.[provided by RefSeq, May 2010]
Synonyms: erythropoietin receptor Antibody , EPO-R Antibody , EPOR Antibody
Cellular Localization:
CAS NO: 256376-24-6
Product: Motesanib (Diphosphate)
Host: Mouse
Clonality: Monoclonal
Isotype: IgG2
Immunogen: Recombinant Human EPO R
Antigen Species: Human
Species Reactivity: Human
Conjugation: Unconjugated
Storage Buffer: PBS
Storage Instruction: Keep as concentrated solution. Aliquot and store at -20ÂșC or below. Avoid multiple freeze-thaw cycles.
Notes: For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Specificity: This antibody recognizes human EPO receptor by WB.
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/25416231?dopt=Abstract
