Product Name: ERAB antibody [5E2]
Applications: FACS, ICC/IF, IHC-P, WB
Predicted Target Size:
Positive Controls:
Form Supplied: Liquid
Concentration:
Purification: Protein A/G purified
Full Name: hydroxysteroid (17-beta) dehydrogenase 10
Background: Functions in mitochondrial tRNA maturation. Part of mitochondrial ribonuclease P, an enzyme composed of MRPP1/RG9MTD1, MRPP2/HSD17B10 and MRPP3/KIAA0391, which cleaves tRNA molecules in their 5-ends. By interacting with intracellular amyloid-beta, it may contribute to the neuronal dysfunction associated with Alzheimer disease (AD).
Synonyms: ABAD, 17bHSD10, 17b-HSD10, MHBD, HSD17B10, ERAB, 17b HSD10
Cellular Localization:
CAS NO: 2044451
Product: BMS-536924
Host: Mouse
Clonality: Monoclonal
Isotype: IgG2a
Immunogen: Full length human recombinant protein of human ERAB (NP_004484) produced in HEK293T cell.
Antigen Species: Human
Species Reactivity: Human, Monkey
Conjugation: Unconjugated
Storage Buffer: PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Storage Instruction: For short-term storage, store at 4°C or aliquot into working amounts and store at -20°C. For long-term storage, store at -70°C (aliquotted). Avoid repeated freeze-thaw cycles.
Notes: For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Specificity: GTX84344 is specific for human ERAB (NP_004484).
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/24852021?dopt=Abstract
