Product Name: ERK1 antibody [E32]
Applications: IP, WB
Predicted Target Size:
Positive Controls:
Form Supplied: Liquid
Concentration: 1 mg/ml (Please refer to the vial label for the specific concentration)
Purification: Protein A purified
Full Name: mitogen-activated protein kinase 3
Background: The protein encoded by this gene is a member of the MAP kinase family. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act in a signaling cascade that regulates various cellular processes such as proliferation, differentiation, and cell cycle progression in response to a variety of extracellular signals. This kinase is activated by upstream kinases, resulting in its translocation to the nucleus where it phosphorylates nuclear targets. Alternatively spliced transcript variants encoding different protein isoforms have been described. [provided by RefSeq]
Synonyms: mitogenactivated protein kinase3, mitogenactivated protein kinase 3, PRKM3, ERK1, mitogen-activated protein kinase 3, P44MAPK, P44ERK1
Cellular Localization:
CAS NO: 1032900-25-6
INT-747
Host: Mouse
Clonality: Monoclonal
Isotype: IgG1
Immunogen: Recombinant full length ERK1 protein
Antigen Species: Human
Species Reactivity: Human, Mouse
Conjugation: Unconjugated
Storage Buffer: 10mM PBS, pH 7.2
Storage Instruction: Store at 4°C (add 0.1% NaN3) for several days to weeks, and at -20°C for longer periods. Avoid repeated freeze-thaw cycles
Notes: For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Specificity: Recognizes only the ERK1 protein (e.g.: from human and mouse cells)
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/24566388?dopt=Abstract
