Product Name: ERK2 antibody (ready-to-use)
Applications: IHC, IHC-P
Predicted Target Size:
Positive Controls: A431 cells, Breast carcinoma
Form Supplied: Liquid
Concentration:
Purification: Immunogen affinity purified
Full Name: mitogen activated protein kinase 1
Background: ERK2 is activated by MEK2, which phosphorylates neighbouring threonine 183 and tyrosine 185 residues. ERK2 is a serine/threonine kinase that phosphorylates MAP2 and myelin basic protein. This kinase is an important proximal componant of the MAP kinase pathway involved in transmitting the signals from growth factors, neurotransmitters and hormones at the cell surface to the transcriptional events in the nucleus.
Synonyms: 116590, ERK2, Mapk1
Cellular Localization: Cytoplasmic
CAS NO: 850664-21-0
AMG 232
Host: Rabbit
Clonality: Polyclonal
Isotype: IgG
Immunogen: Synthetic peptide (unfortunately, the amino acid sequence is considered to be commercially sensitive) (Mouse) (C terminal).
Antigen Species: Mouse
Species Reactivity: Human, Mouse, Rat
Conjugation: Unconjugated
Storage Buffer: PBS, pH 7.4 containing 1%BSA and 0.1% sodium azide
Storage Instruction: Keep as concentrated solution and store at 4°C. Do not freeze.
Notes: For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Specificity:
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/23386399?dopt=Abstract
