Product Name: ITGB3BP antibody
Applications: IHC-P, WB
Predicted Target Size: 20 kDa (note)
Positive Controls:
Form Supplied: Liquid
Concentration:
Purification: Affinity purification
Full Name: integrin beta 3 binding protein (beta3-endonexin)
Background: This gene encodes a transcriptional coregulator that binds to and enhances the activity of members of the nuclear receptor families, thyroid hormone receptors and retinoid X receptors. This protein also acts as a corepressor of NF-kappaB-dependent signaling. This protein induces apoptosis in breast cancer cells through a caspase 2-mediated signaling pathway. This protein is also a component of the centromere-specific histone H3 variant nucleosome associated complex (CENP-NAC) and may be involved in mitotic progression by recruiting the histone H3 variant CENP-A to the centromere. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Sep 2011]
Synonyms: integrin beta 3 binding protein (beta3-endonexin) Antibody , CENPR Antibody , HSU37139 Antibody , CENP-R Antibody , NRIF3 Antibody , TAP20 Antibody
Cellular Localization:
CAS NO: 1404231-34-0
Product: Corosolic acid
Host: Rabbit
Clonality: Polyclonal
Isotype: IgG
Immunogen: Recombinant protein of human ITGB3BP
Antigen Species: Human
Species Reactivity: Human
Conjugation: Unconjugated
Storage Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Storage Instruction: Store at -20°C (regular) or -80°C (long term). Avoid freeze / thaw cycles.
Notes: For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Specificity:
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/21881600?dopt=Abstract
