Product Name: Jagged 1 antibody
Applications: ELISA, ICC/IF, IHC-P, WB
Predicted Target Size:
Positive Controls:
Form Supplied: Liquid
Concentration: 1 mg/ml (Please refer to the vial label for the specific concentration)
Purification: Affinity chromatography purified via peptide column.
Full Name: jagged 1
Background: The jagged 1 protein encoded by JAG1 is the human homolog of the Drosophilia jagged protein. Human jagged 1 is the ligand for the receptor notch 1, the latter a human homolog of the Drosophilia jagged receptor notch. Mutations that alter the jagged 1 protein cause Alagille syndrome. Jagged 1 signalling through notch 1 has also been shown to play a role in hematopoiesis. [provided by RefSeq, Jul 2008]
Synonyms: JAGL1 Antibody , AGS Antibody , AWS Antibody , CD339 Antibody , HJ1 Antibody , AHD Antibody , jagged 1 Antibody , JAG1 Antibody
Cellular Localization:
CAS NO: 6310-41-4
Product: C-7280948
Host: Rabbit
Clonality: Polyclonal
Isotype: IgG
Immunogen: JAG1 antibody was raised against a 19 amino acid peptide near the carboxy terminus of human JAG1.
Antigen Species: Human
Species Reactivity: Human
Conjugation: Unconjugated
Storage Buffer: PBS containing 0.02% sodium azide.
Storage Instruction: Be stored at 4oC for three months and -20oC, stable for up to one year.
Notes: For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Specificity: JAG1 antibody is human reactive. At least two isoforms of JAG1 are known to exist; this antibody will detect both isoforms.
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/20010693?dopt=Abstract
