Product Name: Jagged 1 antibody [C2C3], C-term
Applications: WB-Ag
Predicted Target Size: 134 kDa (note)
Positive Controls: Target recombinant protein
Form Supplied: Liquid
Concentration: 1.04 mg/ml (Please refer to the vial label for the specific concentration)
Purification: Purified by antigen-affinity chromatography.
Full Name: jagged 1
Background: The jagged 1 protein encoded by JAG1 is the human homolog of the Drosophilia jagged protein. Human jagged 1 is the ligand for the receptor notch 1, the latter a human homolog of the Drosophilia jagged receptor notch. Mutations that alter the jagged 1 protein cause Alagille syndrome. Jagged 1 signalling through notch 1 has also been shown to play a role in hematopoiesis. [provided by RefSeq]
Synonyms: AGS antibody, AHD antibody, AWS antibody, CD339 antibody, HJ1 antibody, JAGL1 antibody, MGC104644 antibody, JAG1 antibody, protein jagged-1 antibody, jagged 1 antibody
Cellular Localization: Membrane; Single-pass type I membrane protein
CAS NO: 116714-46-6
Product: Climbazole
Host: Rabbit
Clonality: Polyclonal
Isotype: IgG
Immunogen: Recombinant protein encompassing a sequence within the C-terminus region of human Jagged1. The exact sequence is proprietary.
Antigen Species: Human
Species Reactivity:
Conjugation: Unconjugated
Storage Buffer: 1XPBS, 1% BSA, 20% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
Storage Instruction: Keep as concentrated solution. Aliquot and store at -20ÂșC or below. Avoid multiple freeze-thaw cycles.
Notes: For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Specificity:
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/18997780?dopt=Abstract