Product Name: JNK1 antibody [1E5]
Applications: ELISA, FACS, WB
Predicted Target Size:
Positive Controls:
Form Supplied: Liquid
Concentration: 1 mg/ml (Please refer to the vial label for the specific concentration)
Purification: Protein G Purified
Full Name: mitogen-activated protein kinase 8
Background: The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase is activated by various cell stimuli, and targets specific transcription factors, and thus mediates immediate-early gene expression in response to cell stimuli. The activation of this kinase by tumor-necrosis factor alpha (TNF-alpha) is found to be required for TNF-alpha induced apoptosis. This kinase is also involved in UV radiation induced apoptosis, which is thought to be related to cytochrom c-mediated cell death pathway. Studies of the mouse counterpart of this gene suggested that this kinase play a key role in T cell proliferation, apoptosis and differentiation. Four alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008]
Synonyms: PRKM8 Antibody , JNK Antibody , MAPK8 Antibody , JNK1A2 Antibody , JNK46 Antibody , JNK21B1/2 Antibody , SAPK1 Antibody , SAPK1C Antibody
Cellular Localization:
CAS NO: 891025-25-5
Product: Dicloxacillin (Sodium hydrate)
Host: Mouse
Clonality: Monoclonal
Isotype: IgG1
Immunogen: Purified recombinant fragment of human MAPK8 expressed in E. Coli.
Antigen Species: Human
Species Reactivity: Human, Mouse
Conjugation: Unconjugated
Storage Buffer: PBS, 0.05% sodium azide
Storage Instruction: Keep as concentrated solution. For short-term storage, store at 4° C (up to 10 days). For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Notes: For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Specificity:
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/24806444?dopt=Abstract
