Product Name: Kaiso antibody [2T15]
Applications: GSA, IHC, IP, WB
Predicted Target Size:
Positive Controls: 3T3/A31 cell lysate. Add 2.5µl of 2-mercaptoethanol/100µl of lysate and boil for 5 minutes to reduce the preparation. Load 20µg of reduced lysate per lane for minigels.
Form Supplied: Liquid
Concentration: 1 mg/ml (Please refer to the vial label for the specific concentration)
Purification: Protein G purified
Full Name: zinc finger and BTB domain containing 33
Background: Transcriptional regulator with bimodal DNA-binding specificity. Binds to methylated CpG dinucleotides in the consensus sequence 5-CGCG-3 and also binds to the non-methylated consensus sequence 5-CTGCNA-3. May recruit the N-CoR repressor complex to promote histone deacetylation and the formation of repressive chromatin structures in target gene promoters. Contributes to the repression of target genes of the Wnt signaling pathway. May also activate transcription of a subset of target genes by the recruitment of CTNND2.
Synonyms: AW260253, E130014G12Rik, Kaiso, Znf-kaiso, Znf kaiso, Znfkaiso
Cellular Localization:
CAS NO: 162784-72-7
Product: Dibenzothiophene
Host: Mouse
Clonality: Monoclonal
Isotype: IgG1
Immunogen: Recombinant fusion protein (N-terminal), corresponding to amino acids 103 – 584 of mouse Kaiso.
Antigen Species: Mouse
Species Reactivity: Human, Mouse, Dog, Rat, Hamster
Conjugation: Unconjugated
Storage Buffer: Preservative: 0.05% Sodium Azide; Constituents: 30% Glycerol, 0.15M Sodium Chloride, 0.1M Tris-glycine. pH 7.4
Storage Instruction: stored at 4°C for short-term only. For long-term storage, store at -20°C. Aliquots are stable for at least 12 months at -20°C.
Notes: For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Specificity:
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/20008468?dopt=Abstract
