Product Name: KCNA10 antibody
Applications: WB
Predicted Target Size:
Positive Controls:
Form Supplied: Liquid
Concentration:
Purification: Affinity purified on immobilized antigen.
Full Name: potassium voltage-gated channel, shaker-related subfamily, member 10
Background: Potassium channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. Four sequence-related potassium channel genes – shaker, shaw, shab, and shal – have been identified in Drosophila, and each has been shown to have human homolog(s). This gene encodes a member of the potassium channel, voltage-gated, shaker-related subfamily. This member contains six membrane-spanning domains with a shaker-type repeat in the fourth segment. It is specifically regulated by cGMP and postulated to mediate the effects of substances that increase intracellular cGMP. This gene is intronless, and the gene is clustered with genes KCNA2 and KCNA3 on chromosome 1. [provided by RefSeq, Jul 2008]
Synonyms: Kcn1 Antibody , Kv1.8 Antibody , potassium voltage-gated channel, shaker-related subfamily, member 10 Antibody
Cellular Localization:
CAS NO: 197890-44-1
Product: Dicloralurea
Host: Rabbit
Clonality: Polyclonal
Isotype: IgG
Immunogen: Peptide (C)KDPETLLPTNDIHR, corresponding to amino acid residues 187- 200 of human KV1.8 (Accession Q16322). Intracellular, N-terminus.
Antigen Species: Human
Species Reactivity: Human, Mouse, Rat
Conjugation: Unconjugated
Storage Buffer: Phosphate buffered saline (PBS), pH 7.4, 1% BSA, 0.05% NaN3.
Storage Instruction: Keep as concentrated solution. Aliquot and store at -20ÂșC or below. Avoid multiple freeze-thaw cycles.
Notes: For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Specificity:
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/26202875?dopt=Abstract
