Product Name: KCNAB2 antibody, C-term
Applications: WB
Predicted Target Size: 41 KDa (note)
Positive Controls: HepG2
Form Supplied: Liquid
Concentration: 0.5-1 mg/ml
Purification: Protein A purified
Full Name: potassium voltage-gated channel subfamily A regulatory beta subunit 2
Background: Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. Four sequence-related potassium channel genes – shaker, shaw, shab, and shal – have been identified in Drosophila, and each has been shown to have human homolog(s). This gene encodes a member of the potassium channel, voltage-gated, shaker-related subfamily. This member is one of the beta subunits, which are auxiliary proteins associating with functional Kv-alpha subunits. This member alters functional properties of the KCNA4 gene product. Alternative splicing of this gene results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Dec 2010]
Synonyms: KCNA2B Antibody , AKR6A5 Antibody , HKVBETA2.1 Antibody , HKVBETA2 Antibody , KV BETA2 Antibody , HKVBETA2.2 Antibody , KCNAB2 Antibody
Cellular Localization:
CAS NO: 827022-33-3
Product: EPZ011989
Host: Rabbit
Clonality: Polyclonal
Isotype: IgG
Immunogen: A synthetic peptide corresponding to a C-terminal region of Human KCNAB2
Antigen Species: Human
Species Reactivity: Human
Conjugation: Unconjugated
Storage Buffer: 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Storage Instruction: Keep as concentrated solution. For short-term storage, store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Notes: For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Specificity:
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/26426996?dopt=Abstract
