Product Name: KDM5A / Jarid1A / RBBP2 antibody
Applications: WB
Predicted Target Size: 192 kDa (note)
Positive Controls: 293T , 293T nuclear extracts
Form Supplied: Liquid
Concentration: 2.11 mg/ml (Please refer to the vial label for the specific concentration)
Purification: Purified by antigen-affinity chromatography.
Full Name: lysine (K)-specific demethylase 5A
Background: The protein encoded by this gene is a ubiquitously expressed nuclear protein. It binds directly, with several other proteins, to retinoblastoma protein which regulates cell proliferation. This protein also interacts with rhombotin-2 which functions distinctly in erythropoiesis and in T-cell leukemogenesis. Rhombotin-2 is thought to either directly affect the activity of the encoded protein or may indirectly modulate the functions of the retinoblastoma protein by binding to this protein. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq]
Synonyms: JARID1A antibody , KDM5A antibody , RBBP2 antibody , RBP2 antibody , lysine demethylase 5A antibody
Cellular Localization: Nucleus , nucleolus
CAS NO: 145040-37-5
Product: Ingenol-5,20-acetonide
Host: Rabbit
Clonality: Polyclonal
Isotype: IgG
Immunogen: Recombinant protein encompassing a sequence within the center region of Human KDM5A / Jarid1A / RBBP2. The exact sequence is proprietary.
Antigen Species: Human
Species Reactivity: Human
Conjugation: Unconjugated
Storage Buffer: 1XPBS, 20% Glycerol (pH7). 0.025% ProClin 300 was added as a preservative.
Storage Instruction: Keep as concentrated solution. Aliquot and store at -20ÂșC or below. Avoid multiple freeze-thaw cycles.
Notes: For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Specificity:
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/17488727?dopt=Abstract