Product Name: KEAP1 antibody [C1C3]
Applications: ICC/IF, WB
Predicted Target Size: 70 kDa (note) (2)
Positive Controls: NT2D1 , IMR32 , MCF-7
Form Supplied: Liquid
Concentration: 1 mg/ml (Please refer to the vial label for the specific concentration)
Purification: Purified by antigen-affinity chromatography.
Full Name: kelch-like ECH-associated protein 1
Background: This gene encodes a protein containing KELCH-1 like domains, as well as a BTB/POZ domain. Kelch-like ECH-associated protein 1 interacts with NF-E2-related factor 2 in a redox-sensitive manner and the dissociation of the proteins in the cytoplasm is followed by transportation of NF-E2-related factor 2 to the nucleus. This interaction results in the expression of the catalytic subunit of gamma-glutamylcysteine synthetase. Two alternatively spliced transcript variants encoding the same isoform have been found for this gene. [provided by RefSeq]
Synonyms: INrf2 antibody, KIAA0132 antibody, KLHL19 antibody, MGC10630 antibody, MGC1114 antibody, MGC20887 antibody, MGC4407 antibody, MGC9454 antibody, KEAP1 antibody, cytosolic inhibitor of Nrf2 antibody, kelch-like ECH-associated protein 1 antibody, kelch-like protein 19 antibody
Cellular Localization: Cytoplasm , Nucleus
CAS NO: 92118-27-9
Product: pGlu-Pro-Arg-MNA
Host: Rabbit
Clonality: Polyclonal
Isotype: IgG
Immunogen: Recombinant protein encompassing a sequence within the C-terminus region of human KEAP1. The exact sequence is proprietary.
Antigen Species: Human
Species Reactivity: Human
Conjugation: Unconjugated
Storage Buffer: 0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
Storage Instruction: Keep as concentrated solution. Aliquot and store at -20ÂșC or below. Avoid multiple freeze-thaw cycles.
Notes: For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Specificity:
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/26134678?dopt=Abstract
