Product Name: Ki67 antibody (ready-to-use)
Applications: IHC-P
Predicted Target Size:
Positive Controls: Breast carcinoma and lymph node
Form Supplied: Liquid
Concentration: Ready-to-use
Purification: Immunogen affinity purified
Full Name: antigen identified by monoclonal antibody Ki-67
Background: Ki67 antigen is the prototypic cell cycle related nuclear protein, expressed by proliferating cells in all phases of the active cell cycle (G1, S, G2 and M phase). It is absent in resting (G0) cells. Ki67 antibodies are useful in establishing the cell growing fraction in neoplasms (immunohistochemically quantified by determining the number of Ki67-positive cells among the total number of resting cells = Ki67 index). In neoplastic tissues the prognostic value is comparable to the tritiated thymidine-labelling index. The correlation between low Ki67 index and histologically low-grade tumours is strong.
Synonyms: KIA
Cellular Localization: Nuclear
CAS NO: 654671-78-0
Product: SP-420
Host: Rabbit
Clonality: Polyclonal
Isotype: IgG
Immunogen: The immunogen corresponding to a region within amino acids 1200 and 1300 of human Ki67.
Antigen Species: Human
Species Reactivity: Human, Rat
Conjugation: Unconjugated
Storage Buffer: PBS, pH 7.4 containing 1% BSA and 0.1% sodium azide
Storage Instruction: Keep as concentrated solution and store at 4°C. Do not freeze.
Notes: For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Specificity:
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/23505570?dopt=Abstract
