Product Name: K-Ras antibody [AT2F8]
Applications: ELISA, FACS, ICC/IF, WB
Predicted Target Size:
Positive Controls:
Form Supplied: Liquid
Concentration: 1 mg/ml (Please refer to the vial label for the specific concentration)
Purification: By protein-A affinity chromatography
Full Name: Kirsten rat sarcoma viral oncogene homolog
Background: This gene, a Kirsten ras oncogene homolog from the mammalian ras gene family, encodes a protein that is a member of the small GTPase superfamily. A single amino acid substitution is responsible for an activating mutation. The transforming protein that results is implicated in various malignancies, including lung adenocarcinoma, mucinous adenoma, ductal carcinoma of the pancreas and colorectal carcinoma. Alternative splicing leads to variants encoding two isoforms that differ in the C-terminal region. [provided by RefSeq, Jul 2008]
Synonyms: KRAS1 Antibody , K-RAS2B Antibody , NS Antibody , K-RAS4A Antibody , RASK2 Antibody , KRAS2 Antibody , K-RAS4B Antibody , CFC2 Antibody , Kirsten rat sarcoma viral oncogene homolog Antibody , KI-RAS Antibody , KRAS Antibody , K-RAS2A Antibody , C-K-RAS Antibody , NS3 Antibody
Cellular Localization:
CAS NO: 354813-19-7
Product: Gastrodenol
Host: Mouse
Clonality: Monoclonal
Isotype: IgG2b
Immunogen: Recombinant human KRAS (1-186aa) purified from E. coli
Antigen Species: Human
Species Reactivity: Human
Conjugation: Unconjugated
Storage Buffer: Liquid. In Phosphate-Buffered Saline (pH 7.4) with 0.02% Sodium Azide, 10% Glycerol.
Storage Instruction: Can be stored at +4C. For long term storage, aliquot and store at -20C. Avoid repeated freezing and thawing cycles.
Notes: For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Specificity: This antibody may cross react with human N-Ras and H-Ras.
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/18640115?dopt=Abstract
