Product Name: Ku80 antibody [N1N3]
Applications: IHC-P, WB
Predicted Target Size: 83 kDa (note)
Positive Controls: A549 , HeLa , HepG2 , HCT116
Form Supplied: Liquid
Concentration: 1 mg/ml (Please refer to the vial label for the specific concentration)
Purification: Purified by antigen-affinity chromatography.
Full Name: X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining)
Background: The protein encoded by this gene is the 80-kilodalton subunit of the Ku heterodimer protein which is also known as ATP-dependant DNA helicase II or DNA repair protein XRCC5. Ku is the DNA-binding component of the DNA-dependent protein kinase, and it functions together with the DNA ligase IV-XRCC4 complex in the repair of DNA double-strand break by non-homologous end joining and the completion of V(D)J recombination events. This gene functionally complements Chinese hamster xrs-6, a mutant defective in DNA double-strand break repair and in ability to undergo V(D)J recombination. A rare microsatellite polymorphism in this gene is associated with cancer in patients of varying radiosensitivity. [provided by RefSeq]
Synonyms: FLJ39089 antibody, KARP-1 antibody, KARP1 antibody, KU80 antibody, KUB2 antibody, Ku86 antibody, NFIV antibody, XRCC5 antibody, ATP-dependent DNA helicase II 80 kDa subunit antibody, CTC85 antibody, TLAA antibody, Ku86 autoantigen related protein 1 antibody, nuclear factor IV antibody, 86 kDa subunit of Ku antigen antibody, thyroid-lupus autoantigen antibody, “Ku autoantigen, 80kDa antibody”, ATP-dependent DNA helicase 2 subunit 2 antibody, DNA repair protein XRCC5 antibody, X-ray repair cross-complementing protein 5 antibody, CTC box-binding factor 85 kDa subunit antibody, CTCBF antibody, lupus Ku autoantigen protein p86 antibody, X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining) antibody
Cellular Localization: Nucleus
CAS NO: 43210-67-9
Product: Tizoxanide
Host: Rabbit
Clonality: Polyclonal
Isotype: IgG
Immunogen: Recombinant protein encompassing a sequence within the center region of human Ku80. The exact sequence is proprietary.
Antigen Species: Human
Species Reactivity: Human
Conjugation: Unconjugated
Storage Buffer: 0.1M Tris, 0.1M Glycine, 20% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
Storage Instruction: Keep as concentrated solution. Aliquot and store at -20ÂșC or below. Avoid multiple freeze-thaw cycles.
Notes: For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Specificity:
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/25183520?dopt=Abstract
