Product Name: Kv2.1 (phospho Ser805) antibody
Applications: WB
Predicted Target Size:
Positive Controls:
Form Supplied: Liquid
Concentration: 1 mg/ml (Please refer to the vial label for the specific concentration)
Purification: Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.
Full Name: potassium channel, voltage gated Shab related subfamily B, member 1
Background: Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. Four sequence-related potassium channel genes – shaker, shaw, shab, and shal – have been identified in Drosophila, and each has been shown to have human homolog(s). This gene encodes a member of the potassium channel, voltage-gated, shab-related subfamily. This member is a delayed rectifier potassium channel and its activity is modulated by some other family members. [provided by RefSeq, Jul 2008]
Synonyms: KV2.1 Antibody , EIEE26 Antibody , potassium channel, voltage gated Shab related subfamily B, member 1 Antibody , KCNB1 Antibody , h-DRK1 Antibody , DRK1 Antibody
Cellular Localization:
CAS NO: 1297222
Product: DOTA derivative
Host: Rabbit
Clonality: Polyclonal
Isotype: IgG
Immunogen: Peptide sequence around phosphorylation site of serine805(P-T-S(p)-P-K) derived from Human Kv2.1 .
Antigen Species: Human
Species Reactivity: Human
Conjugation: Unconjugated
Storage Buffer: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Storage Instruction: Store at -20˚C/1 year
Notes: For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Specificity: The antibody detects endogenous level of Kv2.1 only when phosphorylated at serine 805.
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/27100430?dopt=Abstract
